The BRADLEY DEPARTMENT of ELECTRICAL and COMPUTER ENGINEERING

Jason Jianhua Xuan | ECE | Virginia Tech

ECE PROFILE

Jason Jianhua Xuan

Picture of Jason Jianhua Xuan

Office:
Virginia Tech Research Center - Arlington

Mailing Address:
Virginia Tech Research Center - Arlington
Room 4-030900 N. Glebe Road
Arlington, VA 22203

(571) 858-3151
(571) 858-3015
xuan@vt.edu


Education:

Ph.D., Electrical Engineering, University of Maryland, USA, 1997
Ph.D., Electrical Engineering, Zhejiang University, China, 1991
M.S., Electrical Engineering, Zhejiang University, China, 1988
B.S., Electrical Engineering, Zhejiang University, China, 1985

Teaching Interests:

Deep learning, digital image processing, medical imaging and image analysis, multimedia signal processing, computer vision, statistical learning for bioinformatics, computational systems biology, machine learning, information visualization, computer graphics, pattern recognition, and information retrieval.

Research Interests:

Deep genomics, computational systems biology, bioinformatics for cancer research, advanced medical image analysis, and image guided radiation therapy.

Grants and Projects:
  • Uncovering Estrogen Receptor-Signaling Networks to Overcome Endocrine Resistance (NIH/NCI R01CA149653; PI)
  • Transgenerational Effects of Maternal High Fat Diet During Pregnancy of Breast Cancer (NIH/NCI R01CA164384; Co-PI)
  • Collaborative research in integrative cancer biology (NIH/NCI U01CA184902; Co-I)
Selected Publications:
  • Title: ChIP-BIT: Bayesian inference of target genes using a novel joint probabilistic model of ChIP-seq profiles
    Author(s): X. Chen, J.-G. Jung, A. N. Shajahan-Haq, R. Clarke, I.-M. Shih, Y. Wang, L. Magnani, T.-L. Wang, and J. Xuan*
    Journal: Nucleic Acids Res. (Impact Factor (IF) = 10.162), 44(7):e65, 2016
  • Title: Identifying protein interaction subnetworks by a bagging Markov random field-based method
    Author(s): L. Chen, J. Xuan*, R. B. Riggins, Y. Wang and R. Clarke
    Journal: Nucleic Acids Res. (IF = 8.808), 41(2):e42, 2013
  • Title: SprseIso: A novel Bayesian approach to identify alternatively spliced isoforms from RNA-seq data
    Author(s): X. Shi, X. Wang, T.-L. Wang, L. Hilakivi-Clarke, R. Clarke, and J. Xuan*
    Journal: Bioinformatics (IF = 7.307; 2016 ISI), 2017
  • Title: DM-BLD: Differential methylation detection using a hierarchical Bayesian model exploiting local dependency
    Author(s): X. Wang, J. Gu, L. Hilakivi-Clarke, R. Clarke, and J. Xuan*
    Journal: Bioinformatics (IF = 7.307; 2016 ISI), 33(2):161-168, 2017
  • Title: PSSV: A novel pattern-based probabilistic approach for somatic structural variation identification
    Author(s): X. Chen, X. Shi, L. Hilakivi-Clarke, A. N. Shajahan-Haq, R. Clarke, and J. Xuan*
    Journal: Bioinformatics (IF = 7.307; 2016 ISI), 33(2):177-183, 2017
  • Title: BMRF-Net: a software tool for identification of protein interaction subnetworks by a bagging Markov random field-based method
    Author(s): X. Shi, R. O. Barnes, L. Chen, A. N. Shajahan-Haq, L. Hilakivi-Clarke, R. Clarke, Y. Wang, J. Xuan*
    Journal: Bioinformatics (IF=5.766), 31(14):2412-2414, 2015
  • Title: Robust identification of transcriptional regulatory networks using a Gibbs sampler on outlier sum statistic
    Author(s): J. Gu, J. Xuan*, R. B. Riggins, L. Chen, Y. Wang, and R. Clarke
    Journal: Bioinformatics (IF=5.323), 28(15):1990-1997, 2012
  • Title: Definition of NOTCH3 target genes in ovarian cancer
    Author(s): X. Chen, M. M. Thiaville, L. Chen, A. Stoeck, J. Xuan*, M. Gao, I.-M. Shih, and T.-L. Wang
    Journal: Cancer Research (IF = 8.650), 72(9):2294-2303, 2012
  • Title: Identifying cancer biomarkers by network-constrained support vector machines
    Author(s): L. Chen, J. Xuan*, R. B. Riggins, R. Clarke, and Y. Wang
    Journal: BMC Systems Biology (IF = 3.15), 5:161, 2011
  • Title: Multilevel support vector regression analysis to identify condition-specific regulatory networks
    Author(s): L. Chen, J. Xuan*, R. B. Riggins, Y. Wang, E. P. Hoffman, and R. Clarke
    Journal: Bioinformatics (IF = 4.877), 26(11):1416-1422, 2010